Role of T cells during the cerebral infection with Trypanosoma brucei.
The infection by Trypanosoma brucei brucei (T.b.b.), a protozoan parasite, is characterized by an early-systemic stage followed by a late stage in which parasites invade the brain parenchyma in a T cell-dependent manner.Here we found that early after infection effector-memory T cells were predominant among brain T bundle cells, whereas, during the